prevalence of chlamydia trachomatis infection among Saudi women attending the infertility clinic in central Saudi Arabia

To determine the prevalence of Chlamydia trachomatis [C. trachomatis] infection among Saudi women, its clinical presentation, and its association to infertility. This study was conducted between October 2012 and July 2013 at King Khalid University Hospital and King Abdulaziz University Hospital, Riyadh, Kingdom of Saudi Arabia. Female patients aged between 19 and 46 years old with infertility problems seen at both hospitals were recruited to join the study. A separate group of female patients without infertility problems was also recruited from both hospitals to serve as controls for the study. Endocervical swabs were collected from both groups of patients, and samples were analyzed using real time polymerase chain reaction. There was a statistically significantly greater prevalence of C. trachomatis infection in infertile women [n=8, 8.0%] compared with the fertile group of women [n=1, 1.0%]. The C. trachomatis infection was significantly correlated to infertility. A significant association between infertility and increased prevalence of C. trachomatis infection is shown in this study, thus, we suggest that screening for Chlamydial infection to be part of the routine investigation for infertility

Coasting a viable option for patients at risk of ovarian hyperstimulation syndrome

To present our experience in 48 coasted patients and how they performed in terms of the number of eggs collected, numbers of embryos available for embryo transfer after in vitro fertilization, pregnant and on going pregnancy rate. The study was conducted at Lister Hospital, London, United Kingdom, during the period October 1998 through to May 2001. For the purpose of the study, we selected coasted cycles in patients who were less than 38 years of age [n=48 patients]. A control group of cycles consisted of all cycles during the same period in patients less than 38 years of age, who were not coasted because they did not fulfil the at risk criteria, but yet we collected 20 oocytes or more [n=115 cycles, 113 patients]. The study showed that there is no significant difference in outcome between the 2 groups [52.1% pregnancy rate in the coasted group versus 51.3% in the control group]. The incidence of severe ovarian hyperstimulation syndrome was 4.3% in the study group versus 12.2% in the control but this did not reach statistical difference. We therefore conclude that coasting is a safe and viable option for patients at risk of ovarian hyperstimulation syndrome in an assisted conception cycle that allows the transfer of fresh embryos